Our Faculty Members

cckuo

Name: Chung-Chih Kuo (郭昶志)
Title: Associate Professor
Highest Degree: Ph. D.
Research expertise: Electrophysiology, Neuroscience
E-mail: cckuo@mail.tcu.edu.tw
Web site: http://cckuosneurolab.weebly.com/english.html
Office/ Laboratory Site: D807/D815
Office/ Laboratory Tel.:+886-3-8565301 #2713/ 2714
Research Interests:cortical representation of pain, central mechanism of pain manipulation, neuronal plasticity of drug abuse (more)

guofangName: Tseng, Guo-Fang (曾國藩)
Title:
Vice president,
Dean, Research and Development,
Director, Medical Simulation Center,
Professor of Anatomy
Tzu Chi University
Highest Degree: PhD
Research expertise:Cortical neuronal plasticity, Neurotrauma, Neural degeneration and regeneration
E-mail: guofang@mail.tcu.edu.tw
Web site: http://neuroanatomylab.weebly.com/index.html
Office/ Laboratory Site: F320-1
Office/ Laboratory Tel.: +886-3-8565301#7162
Research Interests: In general, the lab focused on 3 areas of interests.1.Trauma and diseases often compress the brain and impair cortical functions. Compression exerts mechanical and chemical influences on underlying cortical neurons. Changes in the underlying cortex were rapid and dramatic and persisted over protracted period of time. Contralateral cortex is expected to be affected overtime as well. In the clinic, compression is often left untreated for example asymptomatic meningioma is usually observed for an extended duration before treatment decision. The fact that delay of decompression is a norm in the clinic intrigued us to investigate the resulted cortical changes and whether these are reversible upon decompression. A plethora of morphological and biochemical techniques were adopted in the quest. In particular, specially configured up-right fixed-staged fluorescence microscope was used to visually guide intracellular dye injection and a PC-based software fitted to a microscope with motorized stage control was used to trace the reveal neurons for 3-dimensional studies.2.The plasticity of cerebral cortex under normal aging. The effect of sex hormones, in particular, on cortical neuronal dendritic spines are scrutinized.3.The efficacy of different approaches of the neurorrhaphy of peripheral nerves following injury as well as investigation on the means to facilitate the recovery.(more)

cjlaiName: Ching Jung Lai (賴靜蓉)
Title: Professor
Highest Degree: Institute of Physiology, National Yang Ming University, Taiwan, Ph.D.
Research expertise: Respiratory Physiology, Neuroscience
E-mail: cjlai@mail.tcu.edu.tw
Web site: http://tcucjlai.weebly.com/ching-jung-lai.html
Office/ Laboratory Site: D536/D530
Office/ Laboratory Tel.:+886-3-8565301 #2133/#2121
Research Interests: Research interest is at the field of respiratory physiology. In our lab, major research programs include 1) the mediator mechanism underlying the hypersensitivity of lung vagal C fibers (LVCFs), a major type of lung vagal sensory receptors, in intermittent hypoxia-exposed rats and 2) gender differences in development of airway hyperreactivity by intermittent hypoxia. Long-term exposure to intermittent hypoxia, such as that occurring in association with obstructive sleep apnea (OSA), may be one factor leading to various cardiorespiratory consequences in patients with OSA. Our previous studies demonstrated that acute intermittent hypoxia sensitizes LVCFs in rats resulting in exaggerated airway reflexogenic responses to chemical stimulants possibly via action of reactive oxygen species and activation of TRPA1 receptors. In addition, we found gender difference exists in IH-induced airway hyperreactivity in rats, and female gonadal hormones may negatively modulate the development of patients with reactive airway diseases associated with OSA. (more)


krshiehName: Shieh, Kun-Ruey (謝坤叡)
Title: Professor
Highest Degree: Ph. D.
Research Expertise: Chronobiology, Neuroscience, Energy Metabolism
E-Mail: krshieh@mail.tcu.edu.tw
Web Site: http://tcukrshieh.weebly.com/dr-shieh-kun-ruey.html
Office/Laboratory Site: D808/D826
Office/Laboratory Tel: +886-3-8565301 #2710/#2712
Research Interests: Our research team is focusing on the investigation of circadian-clock systems. The metabolic, endocrine, and behavioral functions of living organisms are intimately tied to environmental periodicity caused by self-rotation of the earth. All eukaryotes have internal timing mechanisms, i.e. the circadian-clock systems, which generate physiological and behavioral rhythms that can be synchronized to the 24 h environmental cycle. These circadian-clock systems maintain timing harmony between the organism and its environment and circadian timing is a highly conserved feature during the evolution and serves the vital role by matching numerous physiological functions to anticipated environmental demands.An all-comprehensive principle to have emerged from studies of circadian-clock systems and energy balance is that both of these dynamic processes exhibit a hierarchical organization in which the brain drives the function of peripheral tissues. Studies suggest that such interconnections also extend to co-regulation of metabolic and circadian-clock transcription networks within individual peripheral tissues and cells. Recent results suggest that a reciprocal relationship exists between the circadian-clock systems and metabolic pathways.       Therefore, we have focused on the following issues related to the circadian-clock systems.
1. Effects of chronic high-fat diet on circadian-clock systems
2. Circadian-clock systems affected by the insulin resistance
3. Effects of jet lag or circadian disruption on the circadian systems and energy metabolismMoreover, we have some cooperation with clinical issues to do the translational researches on patients with gastro-esophageal reflux disease, schizophrenia or epilepsy.(more)

 

hlinName: Hsun-Hsun Lin (林恂恂)
Title: Associate Professor
Highest Degree: University of Toledo, College of Medicine (formerly Medical College of Ohio), Ph. D.
Research expertise: Neuropharmacology, Electrophysiology
E-mail: hlin@mail.tcu.edu.tw
Web site: http://hlin.tcu.edu.tw/detail.php?recordID=14
Office/ Laboratory Site: D506/D515
Office/ Laboratory Tel.: +886-3-8565301 #2124
Research Interests: central regulation of cardiovascular function (more)


peihsin

Name: Pei-Hsin Liu (劉培新)
Title: Associate Professor
Highest Degree: Ph.D.
Research expertise: Neuroscience, Neurobiology
E-mail: peihsin@mail.tcu.edu.tw
Web site:  http://www.neuron.tcu.edu.tw/study.html and http://www.neuron.tcu.edu.tw/achievement.html
Office/ Laboratory Site: F319 / F313-1
Office/ Laboratory Tel.: +886-3-8565301 #2148 / #2143
Research Interests: Our laboratory is organized according to two themes, both in the broad area of the structure, function and pathology of nervous system. Over the years, we have engaged in studies that chart the relationship between oxidative stress and nerve degeneration/regeneration, and we spent many years unveiling the role of nitric oxide in axotomized motoneurons, including their cell bodies and processes. In recent years, we have been engaging in investigation of thalamocortical connections and cerebral microvasculature in response to brain trauma. Also, we explored the role of free radicals in these pathophysiological processes. (more)

hchoName: Han-Chen Ho (何翰蓁)
Title: Associate Professor
Highest Degree: Ph.D.
Research expertise: Reproductive Biology, Electron Microscopy, Microbial Ecology
E-mail: hcho@mail.tcu.edu.tw
Web site: http://tcuhcho.weebly.com/english.html
Office/ Laboratory Site: F318/ F311
Office/ Laboratory Tel.: +886-3-8565301#2147/ #2159
Research Interests: Gut microbial ecology, Spermatogenesis and sperm motility (more)

Name: Kun-Ta Yang (楊昆達)
Title: Assistant Professor
Highest Degree: Ph.D.,National Taiwan University.
Research expertise: Physiology, Cell physiology
E-mail: ktyang@mail.tcu.edu.tw
Web site: http://tcuktyang.weebly.com/30740313502510426524.html
Office/ Laboratory Site: D504/D514
Office/ Laboratory Tel:+886-3-8565301#2127/ #2126
Research Interests: intracellular ion regulation, free radical, cell death, cell proliferation, cell differentiation (more)

zfyuanName: Zung-Fan Yuan (袁宗凡)
Title: Assistant professor
Highest Degree: PhD
Research expertise: Neuroendocrine, Stress, Reward system
E-mail: zfyuan@mail.tcu.edu.tw
Web site: http://zfyuan.weebly.com/30740313502510426524.html
Office/ Laboratory Site: D505/D513
Office/ Laboratory Tel.: +886-3-8565301 #2128/ #2129
Research Interests: When we suffer stress, the nervous and endocrine systems will activate to coordinate organs to cope the disturbance stress makes. The regulation, once, out of control, our body would meet disasters, like hypertension, diabetes mellitus, autoimmune diseases, sterility, and metal disorders. The main of our goal of research includes:1.The mechanism stress responding cell groups interact with the reward circuit: stress is one of the risk factors making us fragile to abused drugs. We not only focus on the nervous system, but also its confederate, endocrine system.2.The sexual dimorphism of stress responses: Females show higher stress responses than males. It may depend on the differences of brain structure and/or sex hormones between genders. We try to investigate the mechanism. (more)

chris

Name: Wang, Yueh-Jan (王曰然)
Title: Assistant professor
Highest Degree: Ph. D.
Research expertise: Cortical neuronal plasticity, Neurotrauma, Neural degeneration and regeneration
E-mail: chris@mail.tcu.edu.tw
Web site: http://neuroanatomylab.weebly.com/index.html
Office/ Laboratory Site: F317/ F301. F302
Office/ Laboratory Tel.: +886-3-8565301#2140

lijin

Name: Chen, Li-Jin (陳儷今)
Title: Assistant professor
Highest Degree: Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan, Ph.D.
Research expertise: Neuroscience, Brain plasticity, Neurobiology
E-mail: lijin@mail.tcu.edu.tw
Web site: http://neuroanatomylab.weebly.com/index.html
Office/ Laboratory Site: F322, F305/F306
Office/ Laboratory Tel.: +886-3-8565301#2520/2144
Research Interests: Our lab is interested in the brain plasticity under pathological conditions such as traumatic brain injury and hydrocephalus. A large part of the research activities focused on using the brain slice intracellular dye injection technique and subsequent 3‐dimensinal reconstruction to study the structural changes under pathological conditions. (more)